NOT KNOWN FACTUAL STATEMENTS ABOUT NR1-SITE

Applying this strategy, Kalbaugh et al. assigned affinity and efficacy roles to positions while in the LBDs from the NR1 and NR2A NMDAR subunits. In situ mutation of residues in direct connection with sure ligand impacted both equally efficacy and affinity, though positions that stabilize the closed cleft conformation and not using a immediate liga